The destruction of a single kind of insulin-producing cell in the pancreas can lead to diabetes — but a study suggests that other cells could be modified to take its place and help to control blood sugar levels.
The results raise hopes that ‘reprogrammed’ insulin-producing cells could be used as treatment for diabetes, but the approach has so far only been tested with human cells in mice studies.
In a study published on 13 February in Nature, researchers report coaxing human pancreatic cells that don’t normally make insulin, a hormone that regulates the amount of glucose in the blood, to change their identity and begin producing the hormone.
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