The first step to understanding how any system works is to identify its parts.
In a pair of papers published Thursday in Cell, researchers from the Mortimer B. Zuckerman Mind Brain and Behavior Institute announced that they identified 50 different types of inhibitory interneurons—neurons that play an important role in regulating movement—in mice spines. This is the first comprehensive classification of spinal inhibitory interneurons.
The researchers also found that types of interneurons cluster and form connections with motor neuron pools, which are groups of motor neurons tied to the movement of a single muscle. This discovery suggests that different interneuron types have distinct purposes related to movement, which could help researchers better understand motor control in the nervous system.
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