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May 4, 2019

Multivascular networks and functional intravascular topologies within biocompatible hydrogels

Posted by in categories: biotech/medical, food, mathematics, space travel

In air-breathing vertebrates, the circulatory and pulmonary systems contain separate networks of channels that intertwine but do not intersect with each other. Recreating such structures within cell-compatible materials has been a major challenge; even a single vasculature system can be a burden to create. Grigoryan et al. show that natural and synthetic food dyes can be used as photoabsorbers that enable stereolithographic production of hydrogels containing intricate and functional vascular architectures. Using this approach, they demonstrate functional vascular topologies for studies of fluid mixers, valves, intervascular transport, nutrient delivery, and host engraftment.

Science, this issue p. 458

Solid organs transport fluids through distinct vascular networks that are biophysically and biochemically entangled, creating complex three-dimensional (3D) transport regimes that have remained difficult to produce and study. We establish intravascular and multivascular design freedoms with photopolymerizable hydrogels by using food dye additives as biocompatible yet potent photoabsorbers for projection stereolithography. We demonstrate monolithic transparent hydrogels, produced in minutes, comprising efficient intravascular 3D fluid mixers and functional bicuspid valves. We further elaborate entangled vascular networks from space-filling mathematical topologies and explore the oxygenation and flow of human red blood cells during tidal ventilation and distension of a proximate airway. In addition, we deploy structured biodegradable hydrogel carriers in a rodent model of chronic liver injury to highlight the potential translational utility of this materials innovation.

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May 4, 2019

Pirates Made Ocean Vortex ‘The Great Whirl’ Inaccessible. So Scientists Studied It from Space

Posted by in category: space

Using satellite data, scientists are tracking the annual formation of an enormous ocean vortex off the coast of Somalia.

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May 4, 2019

SpaceX Dragon Launches NASA Cargo to Space Station, Aces Predawn Rocket Landing

Posted by in category: space travel

The Dragon cargo capsule will arrive at the orbiting lab on Monday morning (May 6).

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May 4, 2019

Man cracks his neck, ends up giving himself a stroke

Posted by in category: futurism

I’m not going to venture a guess as to what percentage of the population regularly cracks their necks, but I have to imagine it’s pretty high. A quick bend left and right is all it normally takes to produce the satisfying “pop,” and for most of us it seems like little more than a harmless habit.

Apparently that’s not the case, and the story of one 28-year-old Oklahoma man is a strong reminder that toying with one’s own spine can be a dangerous thing. A simple neck crack is all it took to turn Josh Hader’s life upside down, and he knew within moments that he had accidentally done some serious damage.

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May 4, 2019

Anti-CRISPR molecules discovered that can block the gene editing technology

Posted by in categories: bioengineering, biotech/medical, habitats

As we dive into the brave new world of gene editing, CRISPR technologies are undoubtedly becoming increasingly precise, but alongside enhanced precision is also the necessity for developing ways to inhibit or block the process – an anti-CRISPR molecule, if you will. New work from the Broad Institute and Brigham and Women’s Hospital has presented a study that homes in on small molecules that may have the ability to safely block the CRISPR gene editing process.

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May 4, 2019

NASA and Star Wars: The Connections Are Strong in This One

Posted by in categories: robotics/AI, space

#StarWarsDay #StarWars #StarWarsCelebration #NASA #MayThe4thBeWithYou


Space Screening, ‘TIE’-ins, Tatooine and The Droids You’re Looking For

NASA astronauts “use the force” every time they launch … from a certain point of view. We have real-world droids and ion engines. We’ve seen dual-sun planets like Tatooine and a moon that eerily resembles the Death Star. And with all the excitement around the premiere of Star Wars: The Force Awakens, the Force will soon be felt 250 miles above Earth on the International Space Station. Disney is sending up the new film so the astronauts can watch in orbit, and the station’s commander, Scott Kelly, can hardly wait:

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May 4, 2019

How to think about… The multiverse

Posted by in category: cosmology

The multiverse isn’t a hypothesis – it’s a prediction of our best theories of reality.

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May 4, 2019

SpaceX Dragon Heads to Space Station After Successful Launch

Posted by in category: space travel

Success! This morning, SpaceX’s Dragon spacecraft launched from Cape Canaveral Air Force Station in Florida on a mission to deliver more than 5,500 pounds of scientific research, supplies and hardware to the crew aboard the International Space Station. Get the details: https://go.nasa.gov/2vLx99b

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May 4, 2019

The Air Force Just Shot Down Multiple Missiles With A Laser Destined For Fighter Aircraft

Posted by in category: military

The service wants this game-changing capability to be hanging off the wings of fighter jets by the early 2020s.

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May 4, 2019

The Otso Incident with Donovia in 2030

Posted by in categories: computing, finance, geopolitics, treaties

“If we don’t study the mistakes of the future, we’re doomed to repeat them the first time :(” — Ken M, comedian.

[Editor’s Note: Today’s blog post is an excerpt from Mr. Robert J. Hranek’s short story entitled “Angry Engineer,” submitted to the 2019 Mad Scientist Science Fiction Writing Contest. The underlying premise of this contest was that, following months of strained relations and covert hostility with its neighbor Otso, Donovia launched offensive combat operations against Otso on 17 March 2030. Donovia is a wealthy nation that is a near-peer strategic competitor of the United States. The U.S. is a close ally of Otso and is compelled to intervene due to treaty obligations and historical ties. Among the many future innovations addressed in his short story, Mr. Hranek includes a “pre-mortem” in the form of two dozen lessons learned, identifying potential “mistakes of the future” regarding the Battle for Otso, so that we’re not “doomed to repeat them the first time!” Enjoy!]

The U.S. responded to Donovia’s invasion of Otso by initiating combat operations against the aggressors on 1 April 2030 — April Fools’ Day. Thousands of combatants died on both sides, mostly on ships; hundreds more were wounded, primarily from the land battle, and an unverifiable number of casualties occurred worldwide due to the sabotage of power grids and other infrastructure. An accurate civilian count was impossible in the chaos of reestablishing power, computer, and financial systems worldwide.

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